良性肿瘤和恶性实体瘤患者血浆 Lp (a)和其它脂类的变化
The Plasma Level of Lp (a) and other Lipids in Patients with Benign Tumors and Malignant Parenchymatous Tumors
-
摘要: 本文对57例良性肿瘤、52例恶性实休瘤患者和80例正常人血浆中Lp(a)和TC, TG, ApoB, ApoA-I的水平进行了比较。结果发现，上述指标在良性肿瘤与正常人之间无统计学差异。恶性实体瘤患者的LpAbstract: The plasma Level of lipoprotein (a) (Lp (a)):total cholesterdol (TC)，triglyceride (TG)，Apolipoprotein B (ApoB) and ApolipoproteinA一I (ApoA一I) in 57 patients with benign tumors，52 patients }"ith malignant parenchymatous tumors and 80 normal controls were observed. The re-suits showed that there were no statistic differences of the indices observed between benign tumorpatients and normal controls. Patients with malignant parenchymatous tumors had a higher Lp(a) and a Lower TC level compared with that in the other two groups，and a lower level of ApoB and ApoA一I with that in normal controls. It is considered that Lp (a) might excert a certain pro-motive effect on the growth and metastasis of tumors by affects the coagulating system. It is possi-ble that Lp (a) and TC might be used as biochemical indices in accessory diagnosis of malignant tu-morn.The relationship between tumors and Lipids，Lipoproteins or apoLipoproteins is worth fur-ther study.
-
Key words:
- Lp (a) /
- Benign tumor /
- Malignant parenchymatous Tumor /
- Cholesterol
-
-
1 Krempler F. et al. J Clin Invest, 1980, 65 (6)，1483 2 Krempler F, et al. J Clin Invest, 1983, 71，1431 3 Mclean ]W, et al. Nature, 1987, 300:132 4 Edelberg JM, et al. Thromb Res, 1990, 57 (1)，155 5 Brown JM, Cancer Res, 1973, 33，1217 6 Honn KV, et al. Biochen Pharmacol, 1983, 32:1 7 AL一Mondhiry H. Am J Hematology, 1984, 16，193 8 Vitol S, et al. Blood, 1984，63:1186 9 Rudling [M]，et al. Br Med J, 1986, 292:580
计量
- 文章访问数: 1297
- HTML全文浏览量: 41
- PDF下载量: 213
下载:
