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河北省赞皇县居民胃癌高发与幽门螺旋菌感染的相关性研究[J]. 肿瘤防治研究, 1995, 22(2): 110-112.
引用本文: 河北省赞皇县居民胃癌高发与幽门螺旋菌感染的相关性研究[J]. 肿瘤防治研究, 1995, 22(2): 110-112.
A study on the relationship between the high incidence of gastric carcinoma and the infection of Helicobacter Pylori[J]. Cancer Research on Prevention and Treatment, 1995, 22(2): 110-112.
Citation: A study on the relationship between the high incidence of gastric carcinoma and the infection of Helicobacter Pylori[J]. Cancer Research on Prevention and Treatment, 1995, 22(2): 110-112.

河北省赞皇县居民胃癌高发与幽门螺旋菌感染的相关性研究

A study on the relationship between the high incidence of gastric carcinoma and the infection of Helicobacter Pylori

  • 摘要: 本研究应用Warthin-starry染色对414例取自河北省胃癌死亡率较高的赞皇县山区居民(37.8/10万)胃窦部小弯侧近幽门处之胃粘膜进行了幽门螺旋菌(Helicobacterpylori,Hp)的检测。检出率为37.5%,在此基础上汇集了国内3个省共4个县受检人群的检出率进行回归统计,结果其相关系数高达0.963,Y=1.37X-11.91,P<0.05.表明人群中的HP的检出率与胃癌年死亡率之间高度相关,可视为胃癌病因研究的线索。

     

    Abstract: The biopsy specimens of 414 cases who live in the Zan Huang county of Hebei were examined for Helicobacter Pylori (HP) by Warthin-Starry stain.These specimens were taken from gastric mu-cosa in the lesser curvature of pyloric antrum.In this county, the death rate of gastric carcinoma per annum was about 37.8 100, 000.The positive rate of HP was 36.50a" At the same period, we gath-eyed and analysed the data of HP infection from four counties of three provinces.the results show that the regression coefficient (b) is 1.37, the correlation coefficient (r) is 0.9, the standard error (Sx) is 12.7% It is indicated that there is close correlation between the higher incidenoce of gastric carcinoma and the positive rate of HP examined in the various regions.Therefore,the study will give an important clue to the pathogenetic and the development of gastric carcinoma.

     

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