345例Ⅲ期胃癌术前、术后化疗远期疗效对比

The long-term effect of stage if stomach cancer treated by pre and post-operative chemotherapy

摘要: 我院子1975年7月～1988年7月共收治Ⅲ期胃癌345例，皆作根治手术，病理证实。均于术后化疗3～4疗程以上，在回顾性分析中按术后化疗方案选择不同，分为A组（MF）、B组（MFV）、C组（AMF）、D组（UFTM）,我们认为术后化疗选用MF方案疗效高，毒性反应小，且组合简单，药价低廉，疗程时间短，值得推广；术后化疗不宜长程，以-年内完成了3～4疗程化疗为佳；本组资料本前化疗并未能提高生存率，原因有待于进-步探索。

Abstract: 345 patients with stage Yf stomach cancer were treated by radical operation between 1975 and 1987.All cases were given chemotherapy for more than three-four courses after operation.We concluded that MF regime is more effective;less toxity,with simple combination and low price.Also,it can be completed in a short-er time.Post-operative chemotherapy should be considered not to be longer course, it is recommended that 3-4courses are performed in one year.For the reason why pre-operative chemotherapy can not increase the survival,more study is needed.