Abstract: A total of 100 patients with cancer pain were treated with a domestic new analgesic drug-Lysinipinum. The response rate，compoete response rate was 94% and 29% respectively. The remarkable response rate (obvious plus complete) was 82% . The median time for onset of drug effect was 15 minutes and the duration fo analgesic effect was 6. 9 hours. The previous history of using narcotic analgesics for cancer pain obviously influenced the anelgesic effect of the Lysinipinum (Ｐ＜0. 05) but the duration and degree of the pain which the patient experienced did not. The main adverse reaction was sweating of slight and moderate degree in 29 patents.