晚期原发性肝癌腹腔化疗的近期疗效观察

Short Term Effects of Intraperitoneal Chemotherapy for Advanced Primary Hepatic Cancer

摘要: 本文报告了我科从1992年10月以来采用以顺铂为主的腹腔化疗治疗35例晚期原发性肝癌的近期疗效观察。结果：部分缓解12例，有效率34.3%(12/35)，稳定16例，进展7例。毒性反应轻，有轻度恶心、呕吐，对造血机能影响小，对肝肾等没有重大损害。结果表明以顺铂为主的腹腔化疗是有效而毒副反应小的治疗手段。

Abstract: Since October 1992, 35 patients with advanced primary hepatic cancer(PHC)have been treated by Cisplatin-based intraperitoneal chemotherapy.Short term effects:there were 12(34.3%)cases got partial remission, 16 showed no change, and 7 worsened.The toxic effects observed were mild nausea, vomitting and myelosuppression.No toxicity of liver and kidney was observed.It seems that Cisplatinbased intrapertoneal chemotherapy for PHC is well tolerable and active regimen.