Abstract: This paper reported the experience of 10 cases with pelvic exentreration for advanced carcinoma of rectum since 1992 in our hospital.The only occasion we find to do the procedure of pelvic exenteration is in the female with advanced carcinoma of the rectum cancer involving the uretre or the bladder and in the male with the rectum cancer involving the prostate gland, the seminal vesicle or the bladder and the reccurence of carcinoma in the pelvic.The men were 8;the female were 2 of the patients.The operative mortality rate was 0%.The most longest survival time is 3 years and 6 months in this group.Eecept 4th case with postoperative high fever for long time because the pyelonephritis other patients were very well.According the references that this patient has high survival rate of 5-year and this operation is no very difficult and assures a better quality of life, lessening of symptoms, disease control and, in selected patients, a cure, thus we suggest this operation commontly has been accepted for suitable patient.