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盐藻提取物对荷瘤小鼠的抑肿瘤作用[J]. 肿瘤防治研究, 1997, 24(1): 22-23.
引用本文: 盐藻提取物对荷瘤小鼠的抑肿瘤作用[J]. 肿瘤防治研究, 1997, 24(1): 22-23.
Inhibitory Effect of Extracts from Dunaliella Salina (EDS) on Cancerous Rat[J]. Cancer Research on Prevention and Treatment, 1997, 24(1): 22-23.
Citation: Inhibitory Effect of Extracts from Dunaliella Salina (EDS) on Cancerous Rat[J]. Cancer Research on Prevention and Treatment, 1997, 24(1): 22-23.

盐藻提取物对荷瘤小鼠的抑肿瘤作用

Inhibitory Effect of Extracts from Dunaliella Salina (EDS) on Cancerous Rat

  • 摘要: 盐藻提取物(EDS)是海洋甲藻类中提取的一种脂溶性混合物,含有大量胡萝卜素(以卜胡萝卜素为主),还有维生素E及多种不饱和脂肪酸。本实验用荷瘤小鼠(S37)灌胃EDS一个月后,观察对小鼠死亡率及肿瘤抑制率的影响。共做两批,结果相似。高剂量组肿瘤抑制率为10.97%,11.7%,低剂量组为12.53%,18.5%,均比阳性对照药β-胡萝卜素高,但不及阳性对服药环磷酰胺。灌生理盐水组小鼠死亡率为10%,灌EDS组则无死亡。

     

    Abstract: Extracts from Dunaliella Salina (EDS) is a kind of fat-soluble mixture extraced from the allopelagic dunaliella salina. It contains vitamin E and unsaturated fatty acid besides large quantity of carotenoid. We observed the effect on death rate and inhibition rate to cancerous ( S37) rats with EDS therapy for one month. The results of two batches were similar: the inhibition rate in the group of high dosage was 10.97%, 11.7% and in the group of low dosage was 12.53%, 18.5%, Both the in-hibition rates were better than that in group BC (Betacarotene), but were lower than that in Cyclophosphamide group. The death rate was 10% in group of blank control and none of the EDS group was dead.

     

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