Abstract: Eighteen patients with advanced liver cancer treated by embedding drug pumpthrough heapatic artery and portal vein synchron is tically once 4～6weeks. The drug included adriamyc in (ADM), mitomycin(MMC), CarbopLatin(CBP) and Lipodo 1.4 Patients died with in one year and 14 patients surlined more than oneyear. These resultsindicated that he patic arterial and portal vein chemoembol ization could be consideredasan therapy in the manageent of the advanced liver cancer.