Diagnosis Treatment and Prognosis of Prostate Sarcoma (Report of 10 Cases)
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摘要: 目的 探讨前列腺肉瘤的诊断、治疗及预后。 方法 回顾性分析2001年1月~2006年4月我院诊治的10例前列腺肉瘤患者临床资料，同时收集国内40例行手术为主的综合治疗的前列腺肉瘤患者资料进行对比分析。 结果 本组平滑肌肉瘤6例,横纹肌肉瘤4例，6例接受姑息性治疗。姑息性治疗、综合治疗组中位生存时间分别为(8±3.3)月和(21±11.8)月，组间比较差异有统计学意义（P=0.012）。 结论 前列腺肉瘤恶性程度高，预后差，确诊依靠病理。与姑息性治疗相比，综合治疗可提高患者生存率。Abstract: Objective To investigate the diagnosis, treatment and prognosis of prostate sarcoma. Methods During January 2001 and April 2006,the clinical data of ten cases of prostate sarcoma were retrospectively reviewed in our hospital.We researched the recent reports published in China with a total of 64 cases,40 of them had radical surgery followed by chemotherapy and／or radiotherapy. Results Of 10 cases,6 leiomyosarcoma and 4 rhabdomyosarcoma were respectively diagnosed by pathology，6 cases accepted palliative therapy.The median survival time of pallitive therapy group and combined therapy group was (8±3.3)month，(21±11.8)month respectively. The survival rates were significantly difference in two groups(P=0.012). Conclusion Prostatic sarcoma is an aggressive malignancy with a poor prognosis. It can be diagnosed properly based on pathological features. Compared with pallitive therapy,combined therapy can improve survival rate with literature review.
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Key words:
- Prostate sarcoma /
- Diagnosis /
- Treatment /
- Prognosis
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