单次大剂量电子束照射治疗瘢痕的临床研究

Clinical study of the effect of treatment of keloids with once electron beam irradiation in high-dose

摘要: 目的　观察电子束术后单次大剂量照射治疗瘢痕的疗效及皮肤晚期反应。方法　 1 998年 5月至 2 0 0 0年 5月我院收治的 1 0 8例术后瘢痕患者, 随机分成两组。结果　 (1 )研究组瘢痕复发率为 1 1 .1 %(6/5 4), 对照组为 1 2 .9% (7/5 4), 二者比较无统计学意义, P >0 .0 5。 (2 )皮肤晚期损伤, 研究组 1级 4例, 2级 1例 ;对照 1级 3例, 2级 2例, 二者比较均无统计学显著意义, P >0 .0 5。结论　电子束单次大剂量照射是治疗瘢痕的一种有效方法, 耐受性良好, 与传统的分次照射相比, 有治疗周期短, 花费低, 剂量分布好等优点。

Abstract: Objective To Observe the effect of treatment of keloids and late effect of skin with once electron beam irradiation in high-dose. Methods Between May 1999 and May 2000, one hundred and eight patients with keloids after operation were treated in our hospital. They were randomized into two groups. Results 6 patients (11.1%) had keloids recurrence in the study group; 7 patients (12.9%) in the control group, There is no significant difference between two groups ( P >0.05). Grad 1, and Grad2 late effect ...