放疗与化疗对头发表面超微结构的影响

The Effects of Radiotherapy and Chemotherapy on the Superficial Ultrastructure of Hari

摘要: 目的比较放、化疗前后患者头发超微结构改变,探讨放、化疗对头发表面结构的影响。方法用扫描电镜观察18例患者放、化疗前后头发表面超微结构改变,其中10例化疗患者分别采用CEF、CTF、NP方案治疗,8例放疗患者,照射部位分别为:鼻、咽、喉、颈部。结果放、化疗前,毛小皮细胞排列较规则,细胞表面光滑,无明显侵蚀现象;化疗后,接受CEF、CTF治疗者,毛小皮细胞排列不规则,大多数毛小皮翻翘、破裂、粘连、脱落;而NP治疗者,改变较少;放疗后局部毛小皮细胞排列紊乱,几乎都有不同程度的毛小皮翻翘与脱落现象。结论放、化疗前后有较大差异,化疗改变程度重于放疗。

Abstract: Objective To study the effects of radiotherapy and chemotherapy on the superficial ultrastructure of hair by comparing the ultrastructural changes of patients hair before and after radiotherapy and chemotherapy. Methods Observing the superficial ultrastuctural changes of 18 hair samples by scanning electron microscope, 10 of them were from patients who accepted CEF,CTF,NP chemotherapeutic regimen, respectively, 8 of them were from patients who accepted radiotherapy, the irradiated sites were nose, throat, ...