中西医结合治疗恶性脑瘤对照观察

A Comprehensive Curative Effect of Malignant Brain Tumors Treated with VM26+MeCCNU and TCM

摘要: 目的　中西医药辩证施治对38例恶性脑瘤的临床疗效与传统的放化疗的疗效对照观察。方法　治疗组38例用VM26+MeCCNU化疗与中医药辨证配合；对照组18例按常规仅作放疗或化疗。结果　治疗组总有效率(CR+PR)76.3%(29/38)，胶质瘤与转移瘤有效率分别为91.6%(22/24)和50%(7/14)。对照组有效率33.3%(6/18)。主要毒副反应为食欲下降，恶心呕吐，骨髓抑制，多为Ⅱ～Ⅲ级。大部分病人通过中药调理，能达到“增效”和“减毒”之目的。结论　运用中医辨证论治配合化疗，治疗恶性脑瘤的综合有效率为76.3%，与传统单一放化疗的疗效33.3%有显著的差异(P＜0.05)。

Abstract: Objective　To study a comprehensive curative effect of malignant brain tumor treated with chemotherapy combining traditional chinese medicine (TCM). Methods 　VM26+MeCCNU with TCM were used in treated group,38 cases.Chemotherapy or radiotherapy was used along in control group, 18 cases. Results 　Total effective rate (CR+PR) was 76.3%(29/38) in treated group, while 33.3%(6/18) in control group only.Among side effects,marrow function disorder and gastrointestinal reaction were most common seen.Most were grade Ⅱ-Ⅲ,which were treated by reducing toxicity and raising effects of TCM. Conclusion 　chemotherapy and TCM in malignant brain tumor has more effective (76.3%)than traditional chemotherapy or radiotherapy(33.3%)along(P＜0.05).