射频消融联合放化疗治疗局部晚期非小细胞肺癌
Combination of Radiofrequency Ablation and Chemoradiotherapy for Treatment of Locally Advanced Non-small Cell Lung Cancer
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摘要: 目的 探讨射频消融联合放化疗治疗局部晚期非小细胞肺癌的疗效。方法 2 0 0 0年 2月至2 0 0 3月 10月采用射频消融联合放化疗治疗局部晚期非小细胞肺癌 4 2例 (综合组 ), 选择同期条件相同采用常规放化疗局部晚期非小细胞肺癌 38例作对照 (常规组 ) ;比较两组病人的KPS、局部复发率、中位生存期、生存率。结果 综合组和常规组的KPS改善率分别为 2 8.5 7%和 10 .5 2 %, 稳定率分别为4 2 .86 %和 36 .84 %恶化率 2 8.5 7%和 5 2 .6 3% ;综合组KPS评分优于常规组 ( χ2 =6 .32, P <0 .0 5 )。原发灶局部复发率综合组显著低于常规组 ( 2 8.5 7%v 5 0 .0 0 % ;χ2 =3.86, P <0 .0 5 ) ;中位生存期综合组 16个月, 常规组 14个月 ;1、2、3年生存率综合组稍高于常规组 6 3.5 3%v 5 3.5 0 %, 31.99%v 2 9.13%, 2 1.33%v 16 .18%。但两组间生存曲线比较无统计学意义 ( χ2 =0 .33,P >0 .0 5 )。结论 射频消融联合放化疗...Abstract: Objective To evaluate the efficacy of combined percutaneous radiofrequency ablation and chemoradiotherapy, performed by using a clustered electrode needle, for treatment of inoperable non small cell lung cancer. Methods Forty two patients with locally advanced non small cell lung cancer(synthetic group) were treated by combination of chemoradiotherapy and percutaneous radiofrequency ablation.From Feb. 2000 to Oct. 2003. The efficacy was compared with those of 38 patients who received conventional chemot...
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