Abstract: Objective To investigate the clinicopathologic features of patients with node-negative metastasis(pN0) colorectal cancer confirmed by routine pathologic examination(H﹠E staining),and their relationship with survival. Methods The clinico-pathologic data of 57 pN0 colorectal cancer patients were analyzed retrospectively.Kaplan-Meier method was used to compare the survival rate,and Cox proportional hazard model was used to assess the independent prognosis factors for pN0 colorectal cancer. Results Serosa of most cases was not involved and the proportion of localized and well2differentiated aden2 carcinoma was higher. The 52year survival rate was 83. 1 %. Conclusion 　Patient s with colorectal cancer without lymph node metastasis may have well prognosis since radical resection was performed. Invasive depth was the independent prognostic factor.