双原发癌45 例临床分析

Clinical Analysis of Multiple Primary Cancers

摘要: 目的　分析双原发癌的发生机制、诊断、治疗和预后, 以提高认识和治疗水平。方法　对 45例双原发癌的临床资料进行了综合分析。结果　本组病例占同期放疗病人的 1 .1 4%, 男女之比为 2 .5∶ 1, 第一、第二原发癌, 发病年龄均集中在 40～ 60岁年龄段, 分别占 73.3%和 66.7%, 且均以肺癌为主, 77.8%出现在第一原发癌治疗后 5年内。发病间期及病种是影响预后的主要因素。结论　多原发癌的治疗和普通原发癌一样, 其疗效不同于复发癌和转移癌。

Abstract: Objective To investigate the mechanism,Diagnosis,treatment and prognosis of multiple primary cancers (MPC) to make improvement of diagnosis and treatment. Methods A total of 45 patients with two primary cancers admitted from 1988 to 1994 were analyzed retrospectively. Results These cases accounted for 1.14% of all the radiotherapy patients in the same period.With sex ratio of male and female 2.5∶1.The onset age of the two primary cancers was mainly centered around 40~60 years,accounted for 73.3% and 66.7%.A l...