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介入电化学治疗食管癌梗阻近期疗效观察[J]. 肿瘤防治研究, 2000, 27(05): 408-410. DOI: 10.3971/j.issn.1000-8578.2428
引用本文: 介入电化学治疗食管癌梗阻近期疗效观察[J]. 肿瘤防治研究, 2000, 27(05): 408-410. DOI: 10.3971/j.issn.1000-8578.2428
Observations of Recent Effect in Electrochemotheropy of Obstruction of Esophageal Carcinoma[J]. Cancer Research on Prevention and Treatment, 2000, 27(05): 408-410. DOI: 10.3971/j.issn.1000-8578.2428
Citation: Observations of Recent Effect in Electrochemotheropy of Obstruction of Esophageal Carcinoma[J]. Cancer Research on Prevention and Treatment, 2000, 27(05): 408-410. DOI: 10.3971/j.issn.1000-8578.2428

介入电化学治疗食管癌梗阻近期疗效观察

Observations of Recent Effect in Electrochemotheropy of Obstruction of Esophageal Carcinoma

  • 摘要: 目的 探索快速解除食管癌梗阻的新疗法。方法 X线透视引导下食管病灶腔内介入铂合金电极,输入一定量单项直流电的电化学疗法。结果 治疗中晚期食管癌38例,CR3例(7.9%),PR28例(73.7%),NC7例(18.4%),有效率81.6%。有效者均于3~7天进食即改善,3~14天进食提高1~3个类别(P<0.01),7~14天食管腔平均增宽3.1倍(P<0.01)。一次性治疗有效缓解期1~6个月不等。结论 该疗法对食管癌梗阻的局部疗效快而显著,尤以缩窄型为佳,可为其快速解除梗阻较好的措施之一,且简便易行。

     

    Abstract: Objective To search for a new method to release the esophageal obstruction rapidly. Methods Electrochemical therapy (EChT) was performed by inserting platinum alloy electrodes into the site of the esophageal carcinoma under x-ray guidance with direct current. Results The recent result in 38 advanced esophageal carcinomas was shown as follows:three (7.9%) of them were CR,28(73.7%)PR,7(18.4%)NC,the total effective rate was 81.6%.The esophageal obstruction was improved within three to seven days after the treatment.The meal grade was increased from one to three ranges winthin three to fourteen days (P<0.01).The average esophageal lumen diameters of 38 cases were widened 3.1 times within seven to fourteen days (P<0.01).The effective relief period of one-shot therapy was from one to six months. Conclusion EChT is one of the most effective methods in the treatment of advanced esophageal carcinoma,especially those of restriction type.

     

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