CA 125 和CEA 在女性腹膜原发浆液性乳头状癌中表达的观察
Observation of the Expression of CA125 and CEA in Peritoneal Primary Serous Papillary Carcinoma in Female
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摘要: 目的 探讨卵巢癌抗原 CA1 2 5和癌胚抗原 (CEA)在女性腹膜原发浆液性乳头状癌鉴别诊断中的意义。方法 应用免疫组织化学 S- P法, 对 6例女性腹膜原发浆液性乳头状癌的腹膜病灶和卵巢病灶同时做 CA1 2 5检测, 对腹膜病灶做 CEA检测。结果 4例腹膜病灶和卵巢病灶均为CA1 2 5阴性表达, 2例单一腹膜病灶或卵巢病灶呈弱阳性表达 ;4例腹膜病灶 CEA阳性表达, 2例阴性表达。结论 CA1 2 5对区别女性腹膜原发浆液性乳头状癌与卵巢原发癌的腹膜转移有一定的鉴别诊断意义和临床应用价值, CEA对腹膜原发癌与上皮性恶性间皮瘤的鉴别无特异性。Abstract: Objective The significance of differential diagnosis of CA125 and CEA in peritoneal primary serous papillary carcinoma(PPSPC) in female were observed. Methods 6 cases of PPSPC were studied with immunohistochemical S-P method,detected the expression of CA125 in both peritoneal and ovarian lesions and CEA only in peritoneal lesion. Results 4 cases were showed no CA125 expression in both peritoneal and ovarian lesion. 2 cases were showed weak CA125 expression only in either peritoneal or ovarian lesion. 4 of ...
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