胃癌MCD/MVD双标记检测及其意义

MCD/MVD were inspected with immunohistochemical double labeled and quantitative analysis in the gastric carcinoma and its significance

摘要: 目的　探讨MCD、MVD与胃癌的关系。方法　免疫组化双标记检测 10 0例胃癌组织中MCD/MVD, 并作定量分析。结果　MCD/MVD≤ 0 .9时, 癌累及浆膜病例较多 ;MCD/MVD >0 .9时, 癌累及浆膜病例较少, 两者比较, P <0 .0 5。结论　MCD/MVD的比值与癌浸润深度相关, 是反映胃癌生物学行为的一个有用指标。

Abstract: Objective To probe into the relationship of mast cell density(MCD), microvessel density(MVD) and gastric carcinoma. Methods Immunohistochemical double labeled method was used for the observation of MCD/MVD in 100 cases of the gastric carcinoma and quantitative analysis. Results Patients of serosa with carcinoma of MCD/MVD ≤ 0.9 were more than of MCD/MVD> 0.9, P < 0.05 . Conclusion A ratio of MCD/MVD was related to invasion depth of carcinoma, which was a useful index of reflecting on biological...