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摘要:
点击化学是最重要的生物正交化学反应，它像“乐高”一样将分子连接起来。点击化学正深刻影响着肿瘤研究，例如修饰肿瘤细胞、设计肿瘤药物、传输肿瘤药物、药物临床前评估和操控免疫细胞。点击化学也将被用于分子发现和靶向治疗，为肿瘤研究提供新方法。
Abstract:As one of the typical bioorthogonal chemistry reactions, click chemistry joins molecules similar to “Lego”. Bioorthogonal click chemistry is used to modify cancer cells, design antitumor drugs, delivery drugs, manipulate immune cells, and help preclinical evaluation. Click chemistry provides a promising approach for discovering molecules and targeting cancer in cancer research.
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Key words:
- Cancer /
- Click chemistry /
- Bioorthogonal chemistry /
- Cancer research
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Competing interests: The authors declare that they have no competing interests.利益冲突声明：所有作者均声明不存在利益冲突。作者贡献：张百红：检索文献、论文撰写岳红云：论文审校
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