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洪子强, 苟文曦, 盛燕楠, 白向豆, 崔百强, 金大成, 苟云久. 达芬奇机器人与电视辅助胸腔镜手术治疗肺癌短期疗效及术后炎性细胞因子变化比较[J]. 肿瘤防治研究, 2023, 50(4): 378-383. DOI: 10.3971/j.issn.1000-8578.2023.22.1144
引用本文: 洪子强, 苟文曦, 盛燕楠, 白向豆, 崔百强, 金大成, 苟云久. 达芬奇机器人与电视辅助胸腔镜手术治疗肺癌短期疗效及术后炎性细胞因子变化比较[J]. 肿瘤防治研究, 2023, 50(4): 378-383. DOI: 10.3971/j.issn.1000-8578.2023.22.1144
HONG Ziqiang, GOU Wenxi, SHENG Yannan, BAI Xiangdou, CUI Baiqiang, JIN Dacheng, GOU Yunjiu. Short-Term Efficacy and Postoperative Inflammatory Cytokine Changes in Lung Cancer Treated with Da Vinci Robot-assisted Versus Video-assisted Thoracoscopic Surgery[J]. Cancer Research on Prevention and Treatment, 2023, 50(4): 378-383. DOI: 10.3971/j.issn.1000-8578.2023.22.1144
Citation: HONG Ziqiang, GOU Wenxi, SHENG Yannan, BAI Xiangdou, CUI Baiqiang, JIN Dacheng, GOU Yunjiu. Short-Term Efficacy and Postoperative Inflammatory Cytokine Changes in Lung Cancer Treated with Da Vinci Robot-assisted Versus Video-assisted Thoracoscopic Surgery[J]. Cancer Research on Prevention and Treatment, 2023, 50(4): 378-383. DOI: 10.3971/j.issn.1000-8578.2023.22.1144

达芬奇机器人与电视辅助胸腔镜手术治疗肺癌短期疗效及术后炎性细胞因子变化比较

Short-Term Efficacy and Postoperative Inflammatory Cytokine Changes in Lung Cancer Treated with Da Vinci Robot-assisted Versus Video-assisted Thoracoscopic Surgery

  • 摘要:
    目的 评估机器人辅助胸腔镜手术(RATS)与电视辅助胸腔镜手术(VATS)治疗肺癌患者的短期疗效及术后炎性细胞因子变化。
    方法 选取270例微创手术治疗的肺癌患者为研究对象,根据患者经济条件和意愿选择手术方式。其中132例患者通过RATS完成手术,138例患者通过VATS完成手术。比较两组患者的临床资料。
    结果 两组患者均成功完成肺癌根治术,无围手术期死亡病例的发生。与VATS组相比,RATS组术中出血量、术后引流时间、术后住院时间、淋巴结清扫枚数和淋巴结清扫组数更具优势(P < 0.05);VATS组手术时间、术后总胸腔引流量和住院费用更具优势(P < 0.05)。两组术后CRP、PCT、IL-6、IL-8、IL-10及TNF-α的水平较术前均升高,RATS组升高幅度小于VATS组。
    结论 RATS治疗肺癌具有技术和短期疗效上的优势,但是伴有高昂的费用。与VATS相比,RATS组术后炎性细胞因子升高幅度更低,对机体的炎性反应更轻。

     

    Abstract:
    Objective To evaluate the short-term outcomes and postoperative inflammatory cytokine changes in patients with lung cancer treated with robot-assisted thoracoscopic surgery (RATS) versus video-assisted thoracoscopic surgery (VATS).
    Methods A total of 270 patients with lung cancer treated by minimally invasive surgery were selected for the study, and the surgical procedures were selected according to the patients' economic conditions and preferences. Among them, 132 patients completed the operation through RATS, and 138 patients completed the operation through VATS. The clinical data of the two groups were compared.
    Results All patients successfully completed radical lung cancer surgery, and no perioperative deaths were reported. Intraoperative bleeding, postoperative drainage time, postoperative hospital stay, number of lymph nodes dissected, and number of lymph nodes dissected groups were more advantageous in the RATS group compared with the VATS group (P < 0.05). In terms of operative time, total postoperative chest drainage, and hospitalization cost, the VATS group had an advantage (P < 0.05). The postoperative levels of CRP, PCT, IL-6, IL-8, IL-10, and TNF-α increased in both groups, compared with preoperative levels, and the increases in the RATS group were lower than those in the VATS group.
    Conclusion RATS offers technical and short-term efficacy advantages for the treatment of lung cancer but comes with the disadvantage of high cost. Post-operative inflammatory cytokine elevation is lower in the RATS group, and inflammatory response to the organism is less severe.

     

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