Abstract: With the extensive use of gastroscopy as well as colonoscopy, the detectable rate of gastroenteropancreatic neuroendocrine neoplasm(GEP-NEN) has increased substantially. In recent years, the nomination, diagnosis and management of GEP-NEN have changed tremendously. Nowadays, the single-mode treatment is unable to bring the greatest benefit to patients. Instead, multidisciplinary comprehensive treatment model for the promotion and regulation of GEP-NEN diagnosis and treatment is of great significance. This paper is an overview of the related articles and latest clinical consensus(2017) both at home and abroad, which improves the identification of these rare tumors. Additionally, it lays the foundation for clinical diagnosis, treatment as well as prognosis of large sample in future.