BRCA突变型乳腺癌的靶向治疗研究进展
Review of Targeted Therapy for Breast Cancer with BRCA Genes Mutation
-
摘要: 乳腺癌是女性最常见的恶性肿瘤，BRCA1/BRCA2是乳腺癌重要的易感基因，与遗传性乳腺癌的发生密切相关，目前BRCA基因突变型乳腺癌的靶向药物治疗是研究的热点。本文主要介绍BRCA基因在乳腺癌中的发生发展关系，并对其相关靶向治疗作一综述。Abstract: Breast cancer is the most common cancer in female malignant tumors. BRCA1 and BRCA2 are the important susceptibility genes, and have a close relationship with the incidence of breast cancer. Currently, the targeted drugs of breast cancer with BRCA mutations become a research hotspot. This article is to sum up the connection between BRCA genes and breast cancer, and review on related targeted therapy methods.
下载:
