Objective To analyze the incidence of upper gastrointestinal cancers in the high incidence area of esophageal cancer in Cixian from 2003 to 2012, and to provide the evidence for the prevention and treatment of cancer.

Methods Patients' information was collected according to malignant cancer registration standard and upper gastrointestinal carcinomas incidence was evaluated. The variation tendency of upper gastrointestinal carcinomas incidence was analyzed using registration information in Cixian registration center from 2003 to 2012. Variation rate of crude incidence rate, Chinese standardized rate and world standardized rate were calculated. Annual percent change(APC) of incidence was estimated by coordinating with adjusted rate linear regression model. At the same time, we analyzed the annual changes of esophageal cancer, gastric cardia cancer, distal gastric cancer incidence.

Results The crude incidence rate of upper gastrointestinal carcinomas was 165.36/100 000 from 2003 to 2012 in Cixian, with declining tendency each year. The average crude incidence rate of esophagus cancer was 108.05/100 000, with declining tendency year by year. The average crude incidence rate of cardiac carcinoma was 31.21/100 000, with increasing tendency year by year. The average crude incidence rate of distal gastric cancer incidence was 26.10/100 000, with increasing tendency in male and declining tendency in female.

Conclusion The incidence of esophagus cancer declines significantly, but it is still at the first place of malignant tumors in Cixian. The incidence of cardiac carcinoma increases obviously, suggesting that the prevention and treatment of upper gastrointestinal carcinomas should emphasize on cardiac carcinoma and distal gastric cancer. Early diagnosis and treatment are very important.