Abstract: Objective To study the clinical experience of intraarterial adjuvant chemotherapy of malignant tumours of bone . Methods Inserted silica gel ductus in inferior epigastrica artery or others. Intraarterial chemotherapy once every week with the Mustargen 30mg to 60mg ( 3 to 6 times ) followed by intravenous chemotheroy. Results The 49 patients have amputation.One patient with osteosarcoma and two patients with giant cell tumour of bone relapse of 23 patients having Limb-sparing surgery. Conclusion The method is...