皮肤Merkel细胞癌3例

Merkel Cell Carcinoma of Skin(3Cases)

摘要: 目的　探讨Merkel细胞癌的诊断、治疗及预后。方法　 1989～ 1999年间, 共收治 3例Merkel细胞癌患者, 均接受扩大性切除术及放疗和或化疗。结果　 3例病例均于术后 5月内复发, 中位存活期 2年。结论　Merekel细胞癌是一种罕见且进展快的皮肤肿瘤。诊断主要依靠病理 (包括免疫组化方法 ), 即使综合治疗后仍有局部复发和远处转移的倾向, 预后差。

Abstract: Objective To discuss the diagnosis,treatment and prognosis of Merkel cell carcinoma(MCC). Methods Three patients undergone MCC during the period of 1989 through 1999 were reviewed retrospectively.All patients received tumor excision and either chemotherapy or radiotherapy or both. Results All patients experienced local recurrence in 5 months.Median survival duration was no longer than 2 years. Conclusion Merkel cell carcinoma is a rare but particularly aggressive form of skin cancer.The diagnosis is mainly tak...