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2021年石家庄市恶性肿瘤流行情况及疾病负担分析

Epidemiological Characteristics and Disease Burden of Malignant Tumors in Shijiazhuang, 2021

  • 摘要:
    目的 分析2021年石家庄市恶性肿瘤流行特征与疾病负担。
    方法 基于石家庄市肿瘤登记处的数据,计算恶性肿瘤的发病和死亡指标,包括粗率、年龄标化率(中国标准与世界标准)及0~74岁累积率,以描述流行特征;同时,通过计算伤残调整寿命年(DALYs)、早死所致的寿命损失年(YLLs)和伤残所致的寿命损失年(YLDs),评估疾病负担。
    结果 2021年,石家庄市共报告新发恶性肿瘤13 250例,粗发病率为275.50/10万(中标发病率177.17/10万,世标发病率172.11/10万),0~74岁累积发病率为17.77%;年龄别发病率在80~84岁年龄组达到峰值。恶性肿瘤死亡7 165例,粗死亡率为148.98/10万(中标死亡率85.13/10万,世标死亡率84.52/10万),0~74岁累积死亡率为9.49%;年龄别死亡率在85岁及以上年龄组最高。肺癌和乳腺癌分别是男性和女性发病率最高的癌种。全年恶性肿瘤总DALYs为87 725.29人年,DALYs率为18.24‰;其中YLLs(85 392.09人年)占总DALYs的97.34%,而YLDs(2 333.19人年)占2.66%。疾病负担最重的为肺癌(DALYs为22 687.12人年,占25.86%),其次为胃癌、肝癌、结直肠癌和食管癌。
    结论 肺癌、肝癌、女性乳腺癌、胃癌及结直肠癌是石家庄市居民所患的主要恶性肿瘤类型,给该市居民造成了沉重的疾病负担。建议依据上述流行特征,尽早实施针对性的重点防控策略。

     

    Abstract:
    Objective To analyze the epidemiological characteristics and disease burden of malignant tumors in Shijiazhuang in 2021.
    Methods Based on data from the Shijiazhuang City Cancer Registry, incidence and mortality indicators for malignant tumors were calculated, including crude rates, age-standardized rates (using Chinese and world standard populations), and the cumulative rate (0−74 years old), to describe the epidemiological profile. The disability-adjusted life years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) were calculated to estimate the disease burden of malignant tumors.
    Results In 2021, a total of 13250 new cancer cases were recorded. The crude incidence rate was 275.50/105, the ASR China was 177.17/105, the ASR world was 172.11/105, and the cumulative rate (0–74 years old) was17.77%. The age-specific incidence of malignant tumors reached its peak in the age group of 80–84 years old. A total of 7165 deaths were noted, and the crude mortality rate was 148.98/105. The ASR China was 85.13/105, the ASR world was 84.52/105, and the cumulative rate (0–74 years old) was 9.49%. The age-specific mortality of malignant tumors reached its peak in the age group of above 85 years old. Lung cancer and breast cancer were the most common malignant tumors in males and females. The DALYs of malignant tumors were 87725.29 person-years, and the DALY rate was 18.24‰. YLL was 85392.09 person-years (97.34%), and YLD was 2333.19 person-years (2.66%). Lung cancer had the heaviest disease burden with DALY of 22687.12 person-years, accounting for 25.86% of all malignant tumors, followed by gastric, liver, colorectal and esophageal cancers.
    Conclusion Cancers of the lung, liver, female breast, stomach, and colorectum are the major health threats in Shijiazhuang. Malignant tumor brings heavy burden to residents of Shijiazhuang city. To decrease the disease burden of cancer, scholars should pay more attention, and implement preventive measures early.

     

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