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2018—2020年云南省昆明市西山区结直肠癌流行病学负担分析

Epidemiologic Burden of Colorectal Cancer in Xishan District, Kunming City, Yunnan Province, 2018—2020

  • 摘要:
    目的 分析2018—2020年云南省昆明市西山区结直肠癌流行病学负担。
    方法 基于国家疾控中心的“肿瘤信息登记报告系统”和“居民死亡原因登记系统”数据,计算该区结直肠癌的发病率、死亡率、年龄别发病/死亡率、潜在减寿年数(PYLL)、伤残调整寿命年(DALY)等流行病学负担指标。
    结果 2018—2020年昆明市西山区结直肠癌中标发病率从25.27/10万增至26.29/10万,中标死亡率从17.11/10万减至16.03/10万;各年PYLL分别为1399.62人年、1376.78人年、1571.56人年,DALY分别为1927.74人年、1875.05人年、1945.17人年;45岁以上男性各项负担指标均高于女性。
    结论 针对昆明市西山区结直肠癌呈现的“发病风险持续存在而死亡率稳步下降”的并行态势,应确立以“生活方式干预—定期筛查—阳性追踪”为核心的三级防控体系,并重点覆盖45岁以上男性高危人群。

     

    Abstract:
    Objective To analyze the epidemiologic burden of colorectal cancer in Xishan District, Kunming City, Yunnan Province from 2018 to 2020.
    Methods Indicators of epidemiologic burden were calculated, including incidence rate, mortality rate, age-specific incidence/mortality rates, potential years of life lost (PYLL), and disability-adjusted life years (DALY) based on the National Disease Control and Prevention Center’s "Cancer Information Registration and Reporting System" and "Cause of Death Registration System".
    Results From 2018 to 2020, the ASR (China) for the incidence of colorectal cancer in Xishan District, Kunming City increased from 25.27/105 to 26.29/105, while the ASR (China) for mortality decreased from 17.11/105 to 16.03/105. The PYLL in 2018–2020 were 1399.63, 1376.78, and 1571.56 person-years, respectively, whereas the DALY in 2018–2020 were 1927.74, 1875.05, and 1945.17 person-years, respectively. The morbidity, mortality, PYLL, and DALY were generally higher in males than in females over 45 years of age.
    Conclusion Given the parallel trends of persistent incidence risk and steadily declining mortality for colorectal cancer in Xishan District, Kunming City, a three-tier prevention and control system centered on "lifestyle intervention–regular screening–positive case tracking" should be established, with a focus on covering high-risk populations, particularly males over 45 years of age.

     

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