Research Progress of CircRNAs Regulating Biological Behavior of Clear Cell Renal Cell Carcinoma

ZHANG Huijie; LIU Liting; CUI Hongwei; YU Lei; YUE Genquan

doi:10.3971/j.issn.1000-8578.2021.21.0493

Cancer Research on Prevention and Treatment > 2021 > 48(8): 814-819. > DOI: 10.3971/j.issn.1000-8578.2021.21.0493

ZHANG Huijie, LIU Liting, CUI Hongwei, YU Lei, YUE Genquan. Research Progress of CircRNAs Regulating Biological Behavior of Clear Cell Renal Cell Carcinoma[J]. Cancer Research on Prevention and Treatment, 2021, 48(8): 814-819. DOI: 10.3971/j.issn.1000-8578.2021.21.0493

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Research Progress of CircRNAs Regulating Biological Behavior of Clear Cell Renal Cell Carcinoma

1.
Clinical Research Center, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China
2.
Department of Pharmacy, Traditional Chinese Medicine Hospital of Inner Mongolia Autonomous Region, Hohhot 010020, China
3.
Department of Urology, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China

Funding:

Natural Science Foundation of Inner Mongolia Autonomous Region 2015MS08115

Natural Science Foundation of Inner Mongolia Autonomous Region 2020LH08031

Health and Family Planning Scientific Research Program of Inner Mongolia Autonomous Region 201701066

More Information

Corresponding author:
YUE Genquan, E-mail: yuegenquan1128@sina.com
Received Date: April 29, 2021
Revised Date: June 29, 2021
Available Online: January 12, 2024

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Abstract

Abstract

Renal cell carcinoma is one of the ten multiple cancers, and its incidence rate and mortality rate have been increasing in more than 20 years. Clear cell renal cell carcinoma (ccRCC) is the most common histopathological subtype. Cyclic ribonucleic acids (circRNAs) are noncoding ribonucleic acids, which are widely distributed with diverse cellular functions and have organ- and tissue-specific expression patterns. Recent studies have shown that circRNAs are abnormally expressed in ccRCC and play an important role in the occurrence and development of ccRCC. However, there are few researches and related mechanisms of circRNAs regulating the biological behavior of ccRCC. Therefore, the paper mainly describes the research progress of circRNAs regulating the biological behavior of ccRCC and discusses its potential as a biomarker for early diagnosis and prognosis of ccRCC and targeted therapy.
- Cyclic ribonucleic acids,
- Clear cell renal cell carcinoma,
- Biological behavior

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Competing interests: The authors declare that they have no competing interests.

References (34)

References

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