Clinical Features and Prognostic Factors of Adenoid Cystic Carcinoma of Head and Neck

WU Fengyang; WU Qiuji; YANG Xiting; ZHONG Yahua

doi:10.3971/j.issn.1000-8578.2022.21.1203

Cancer Research on Prevention and Treatment > 2022 > 49(5): 427-431. > DOI: 10.3971/j.issn.1000-8578.2022.21.1203

WU Fengyang, WU Qiuji, YANG Xiting, ZHONG Yahua. Clinical Features and Prognostic Factors of Adenoid Cystic Carcinoma of Head and Neck[J]. Cancer Research on Prevention and Treatment, 2022, 49(5): 427-431. DOI: 10.3971/j.issn.1000-8578.2022.21.1203

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Clinical Features and Prognostic Factors of Adenoid Cystic Carcinoma of Head and Neck

Department of Cancer Radiotherapy and Chemotherapy, Zhongnan Hospital, Wuhan University, Wuhan 430071, China

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Corresponding author:
ZHONG Yahua, E-mail: doctorzyh73@163.com
Received Date: October 20, 2021
Revised Date: February 08, 2022
Available Online: January 12, 2024

Graphical Abstract

Abstract

Abstract

Objective
To retrospectively analyze the clinical and pathological data of 48 patients with adenoid cystic carcinoma of the head and neck and screen out related factors that affect the patient's prognosis.
Methods
The overall survival rate of patients is used as the main indicator for observing prognosis. We selected 11 clinical and pathological factors as observation indicators that may have an impact on the survival and prognosis of patients. The relation between observation factors and the overall survival rate of patients was analyzed by Cox multivariate regression.
Results
The median follow-up time was 33.5(1-98) months. The 1-, 2- and 5-years overall survival rates were 95%, 91% and 87%. Local recurrence occurred in 14(29.2%) patients. Distant metastasis occurred in 22(45.8%) patients. Cox regression analysis showed that recurrence, distant metastasis and primary site were correlated with the overall survival rate of patients with head and neck adenoid cystic carcinoma (P < 0.05).
Conclusion
Adenoid cystic carcinoma is a relatively rare tumor of the head and neck with a low degree of malignancy. However, recurrence, distant metastasis and primary site have relatively great impact on the prognosis of patients.
- Head and neck neoplasms,
- Adenoid cystic carcinoma,
- Prognosis,
- Multivariate regression analysis

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Competing interests: The authors declare that they have no competing interests

References (23)

References

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Clinical Features and Prognostic Factors of Adenoid Cystic Carcinoma of Head and Neck