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Advances in Treatment of Triple Negative Breast Cancer |
KANG Yikun, YUAN Peng |
Department of VIP Medical Services, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China |
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Abstract TNBC is a special type of breast cancer with strong aggressiveness and poor prognosis. Chemotherapy is still the main treatment for TNBC, due to poor efficacy of endocrine therapy and targeted therapy. However, TNBC is a kind of heterogeneous disease, so it is urgent to study the precise molecular types and explore new precision treatment. This paper will summarize the results of clinical trials and analyze treatment strategies for TNBC, including surgical treatment, radiotherapy, chemotherapy, targeted therapy and immunotherapy, in order to provide evidence for clinical management.
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Keywords
TNBC
BRCA gene
Chemotherapy
Immunotherapy
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Fund:National Natural Science Foundation of China (No. 81672634, 82172650); Beijing Medical Award Foundation (No. YXJL-2020-0941-0763); Beijing Natural Science Foundation (No. 7222150) |
Issue Date: 11 August 2022
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