头颈部肌上皮癌8例报告

Myoepithelial Carcinoma of Head and Neck (a report of 8 cases)

摘要: 目的探讨头颈部肌上皮癌的生物学行为、诊断、治疗及预后。方法回顾性分析8例头颈部肌上皮癌临床资料,并复习文献。结果8例中原发于腮腺3例,颌下腺2例,硬腭1例,鼻腔鼻窦2例。经病理组织学和免疫组织化学确诊。8例均行根治性手术治疗,4例术后局部复发,6例出现远处转移,分别在术后8个月至5年内死亡。5例死于远处转移,3例死于恶液质。结论头颈部肌上皮癌较为罕见,肿瘤生物学行为具有生长迅速、颈部淋巴结转移率高、血行转移率高、治疗后易复发、预后差等特点。该瘤缺乏特征性临床表现,诊断依赖病理和免疫组化。治疗以根治性手术为主,术后可辅以化、放疗。

Abstract: Objective To discuss the biological behavior, diagnosis, treatment, and prognosis of myoepithelial carcinoma in head and neck. Methods Records of 8 patients with myoepithelial carcinoma in head and neck were retrospectively analyzed, at the same time the literatures were reviewed. Results There are 3 cases in parotid gland, 2 cases in submaxillary salivary gland, 1 case in hard palate, 2 cases in nasal cavity and nasal sinus. All cases were exactly diagnosed by pathohistology and immunohistochemistry. All c...