Clinical Study on 33 Cases of Malignant Tumor Complicated with Venous Thrombotic Embolism

Objective To assess the influencing factors,treatment and prognosis of malignant tumor patients with venous thomboembolic events(VIE). Methods The clinical data, including the site of thrombosis,platelet,D-dimer and fibrinogen level,of 33 patients with malignant tumor and VTE were retrospectively analyzed. Results One case complicated with pulmonary embolism(PTE) died within 4 h.Among the other 32 cases with deep venous thrombosis(DVT),11 cases obtained complete response,8 partial response,and 14 progress proceed.D-dimer and fibrinogen increased when VTE occurred.The median survival time of patients with high level D-dimer was 80 d which was lower than those patients with low levels(420 d).They showed significant difference(P=0.026). Conclusion The main treatments of anti-VTE are anticoagulation and anti-assembly.D-dimer,Fibrinogen in the diagnosis and prognosis determination of the patients with VTE are important prognostic factors.