Abstract: Human papillomavirus (HPV) infection is the leading cause of cervical cancer and an important risk factor for genital warts, anal cancer, oropharyngeal cancer, penile cancer, and other diseases. Comprehensive HPV prevention and control has become a public health priority for the whole population. Previous cervical cancer prevention and control systems in China have faced challenges such as poor service coordination and fragmented care processes, predominantly targeting the female demographic. The prevention and management of HPV-related diseases in male have been relatively deficient, resulting in a significant gender gap in the prevention continuum. The Gynaecological Tumor Prevention and Treatment Professional Committee of the Chinese Maternal and Child Health Association organized experts in relevant fields to integrate the latest domestic and international evidence and practical insights, grounded in the functional roles and specialized strengths of maternal and child health institutions, and defined the current integrated strategy of "gender-shared prevention and stage-specific management." Under this strategy, women receive comprehensive closed-loop services covering vaccination, screening, diagnosis, treatment, and whole-process follow-up, whereas men focus on health education, vaccination, and targeted screening and risk assessment for high-risk populations; those with abnormal screening findings or confirmed diagnoses are referred in a standardized manner to specialized departments, such as anorectal surgery, urology, or dermatology, or to general hospitals. This consensus focuses on the construction standards, service processes, and management mechanisms of integrated clinics for HPV prevention and control in both sexes in maternal and child health institutions and refines the optimized pathways for cervical cancer screening, diagnosis, and treatment in females, as well as the standards for HPV-related disease screening and referral in males. It aims to provide practical guidance for maternal and child health institutions at all levels to improve the whole-cycle prevention chain, promote gender-coordinated prevention and control, and accelerate progress toward the elimination of HPV-related disease.