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2007  Vol.34 (Number 9)    
Sept. 25, 2007
  基础研究
  临床研究
  短篇个案
  临床应用
  流行病学
  研究简报
  综述
  技术交流
  论著摘要
 
 
 
 
基础研究
 
 
647 ZHANG Wen-bin, ZHANG Hai-hong, KONG Wei, CHA Xiao, CHEN Ting-qing, DENG Bi-fang, REN Yuan, HUANG Jian-mingSichuan Cancer Hospital amp, Institute, Chengdu , China, Vaccine Research Center, Jilin University and
  Specific Anti-tumor Immunological Effect by Dendritic Cell Transfected with GM-ΔSur Gene
    Objective To study the specific anti-tumor immunological effects induced by dendritic cells transfected with GM-CSF gene and survivin gene(GM-ΔSur) in vitro. Methods pcDNA 3.1 plasmid containing GM-ΔSur fusion gene was constructed and was transfected in...
    2007 Vol. 34 (9): 647-650 [Abstract ] ( 244 ) [HTML 0KB] [PDF 0KB ]( 0 )
651 WANG Yan-yan, SONG Xing-fu, CUI Xiang-jun, HUANG JiThe First College of Clinical Medical Science of China Three Gorges University amp, Yichang Central Peoples Hospital, Yichang and China
  Apoptosis Induced by Artesunate in Human Adenocarcinoma Cell Line A549 Cells Associated with Activation of caspase-9 and caspase-3
   

Objective To investigate the effects of artesunate on apoptosis of human adenocarcinoma cell line A549 cells and activation of cysteine containing aspartate 9(caspase-9) and cysteine containing aspartate 3(caspase-3). Methods A549 cells were treated wi...

    2007 Vol. 34 (9): 651-653 [Abstract ] ( 172 ) [HTML 0KB] [PDF 0KB ]( 0 )
654 LUO Zhi-fen, ZHOU Yun, LIU Ming-yueDepartment of Oncology, Henan Provincial Peoples Hospital, Zhengzhou and China
  Effects of Teniposide on Cell Cycle Phase and Apoptosis of Gastric Carcinoma Cell Lines
    Objective To identify the action mechanism of teniposide on gastric carcinoma cell line BGC-823. Methods The suppressive rate of cell growth of teniposide was examined by MTT assay, the development of cell cycle and apoptosis induced by teniposide was exa...
    2007 Vol. 34 (9): 654-655 [Abstract ] ( 159 ) [HTML 0KB] [PDF 0KB ]( 0 )
656 KANG Ying, LIU Hong-guang, ZENG Gu-qing, GU Yi-xue Department of Surgical, Nnhua University, Hengyang , China, Cancer Center and The First Affiliated Hospital of Nanhua University
  Chrysin Inhibiting Proliferation and Inducing Apoptosis in Gastric Cancer SGC-7901 Cells
   

Objective To study the anticancer function and possible mechanism of Chrysin on gastric cancer cells(SGC-7901).Methods The cells of human gastric cancer cell line SGC-7901 was treated respectively with Chrysin at different concentration 10、20、40、80 ...

    2007 Vol. 34 (9): 656-658 [Abstract ] ( 159 ) [HTML 0KB] [PDF 0KB ]( 0 )
659 LAN Mei, SHI Yong-quan, HAN Zhe-yi, NING Xiao-xuan, FAN Dai-ming Department of Internal Medicine, the Affiliated Hospital of Medical College of Shaoxing University, Shaoxing , China, Institute of Digestive Disease amp, State Key Laboratory of Cancer Biology, Xijing Hospital and Fourth Military Medical University
  Effect of Changes in Intracellular Calcium on Hypoxic Inducible Factor-1 Expression and Transcriptional Activity in Human Gastric Cancer Cells
    Objective To study the possible roles of changed intracellular calcium level in SGC7901 cells on HIF-1α expression and HIF-1 transcriptional activity. Methods Under normoxic conditions, the protein expression of HIF-1α in SGC7901 cells after treatment w...
    2007 Vol. 34 (9): 659-662 [Abstract ] ( 133 ) [HTML 0KB] [PDF 0KB ]( 0 )
663 FAN Hai-tao, WANG Xiu-yan, CHAI Hong-mei, LIU Lu-cheng Department of Urology, The Second Hospital of Jilin University, Jilin , China and Department of Anesthesiology
  Effect of VEGF Antisense Oligonucleotide Combined with Low Molecular Weight Heparin on the Growth and Metastasis of Mice Bladder Cancer
    Objective To investigate the inhibitory effect of vascular endothelial growth factor(VEGF) antisense oligonucleotides or/and dalteparin sodium(fragmin) on tumor growth and metastasis of mice bladder cancer. Methods Forty mice with bladder cancer were rand...
    2007 Vol. 34 (9): 663-666 [Abstract ] ( 134 ) [HTML 0KB] [PDF 0KB ]( 0 )
667 Zeng Zhao-jun, LI Zi-bo, HU Wei-xin, LUO Sai-qun, Chen Qian Molecular Biology Research Center, College of Biological Science and Technology, Central South University, Changsha and China
  可调控重组腺相关病毒对MCF-7细胞基因转染效率及表达的研究
    Objective To explore the treatment of human breast cancer by adeno-associated virus (AAV) expressing HSVtk gene under the regulation of Tet regulatory system, the recombinant AAV-2 were transduced into MCF-7 cell line. Methods The Tet-On and HSVtk gene wa...
    2007 Vol. 34 (9): 667-670 [Abstract ] ( 137 ) [HTML 0KB] [PDF 0KB ]( 0 )
671 YUAN Huai-bo, MI Man-tian, CHEN Zong-dao, WEI Zhao-jun College of Biotechnology and Food Engineering, Hefei University of Technology, Hefei , China, Department of Nutrition and Food Hygene, rd Military and Medical University, College of Food Science and Southwest University
  Effect of Kudzu Flavonoids Extracts on Proliferation and Apoptosis of HL-60 Cells
    Objective To investigate the effect of Kudzu flavonoids extracts on human leukaemia cancer cells HL-60 line to reveal its probable mechanism. Methods The survival and proliferation of HL-60 cells were determined by MTT.The cell-DNA ploidy distribution and...
    2007 Vol. 34 (9): 671-674 [Abstract ] ( 142 ) [HTML 0KB] [PDF 0KB ]( 0 )
675 GUI Fang, ZHANG Zhuo-ran, DUAN Yu-feng, ZHOU Zhi-hang, TENG Lan-ju, LI Zheng-ming Huaihua Medical College, Huaihua , China and Department of Microbiology of Dalian Medical University
  Difference of Apoptosis in Tumer Cells Induced by Influenza A and B Viruses
    Objective To observe and compare the difference of apoptosis in tumer cells induced by different influenza viruses. Methods The shapes of HeLa cells in different time were observed in the electron microscope after they were infected by influenza virus typ...
    2007 Vol. 34 (9): 675-677 [Abstract ] ( 120 ) [HTML 0KB] [PDF 0KB ]( 0 )
678 ZHANG Hai-tao, WU Jun, WANG Ya-jun, GUO Xia, FENG Zhe-ling, LIANG Nian-ci, ZHU Zhen-yu, MA Jian-quan Department of Biochemistry and Molecular Biology, Guangdong Medical College, Zhanjiang , China, Affiliated Hospital of Guangdong Medical College, Department of Biochemistry and Molecular Biology and Zhongshan Medical College of Sun Yat-sen University
  Change of Gene Expression in Raji Cells Induced by Sodium Butyrate
    Objective This study was designed to analyze the change of gene expression and investigate the mechanism of apoptosis induced by sodium butyrate. Methods The change of gene expression was analyzed by Restriction Display PCR (RD-PCR).The differences expres...
    2007 Vol. 34 (9): 678-681 [Abstract ] ( 129 ) [HTML 0KB] [PDF 0KB ]( 0 )
682 CHEN Mu, ZHANG Jian-dong, ZHANG Yu, WANG Xiao-ling, SHEN Wei-gan, LI Guo-qingDepartment of Clinical Diagnostics, The Medical College of Yangzhou University, Yangzhou and China
  Effect of Arsenic Trioxide on Related Factors of Angiogenesis in K562/A02 Cells
    Objective To investigate the effect of arsenic trioxide (As2O3) on the expression of VEGF and the activity of MMP-2 and 9 in K562/A02 cells. Methods MTT assay was used to detect the inhibition ratio of K562/A02 cell. Enzyme-linked immunosorbent assay (ELI...
    2007 Vol. 34 (9): 682-685 [Abstract ] ( 150 ) [HTML 0KB] [PDF 0KB ]( 0 )
临床研究
 
 
686 QIN Gang, , YU Ling, YANG Jin-liang, LI Zu-mao, YANG Hong-bin, WEN Yan-jun, WEI Yu-quan, LIANG Chuan-yu, TIAN Ling Departmant of Otorhinolaryngology and Head amp, Neck Surgery, West China Hospital, Sichuan University, Chengdu , China, Department of Otorhinolaryng ology and Head amp, Neck Surgery, Affiliated Hospital of Luzhou Medical College, Department of Ophthalmology, Division of Cancer Biotherapy and State Key Laboratory of Biotheragy
  Expression of Immunoglobulin M (IgM) in Multiple Epitheliogenic Malignant Tumor Tissue and Carcinoma Cell Lines
    Objective To examine the expression level of immunoglobulin M (IgM) in multiple epitheliogenic malignant tumor tissue and carcinoma cell lines. Methods Tissue microarray and immunohistochemistry were utilized to detect the expression level of IgM in ten e...
    2007 Vol. 34 (9): 686-689 [Abstract ] ( 145 ) [HTML 0KB] [PDF 0KB ]( 0 )
690 XU Wei-li, NIU Ai-guo, LI Suo-lin, SHI Bao-junDepartment of Pediatric Surgery, The nd Hospital of Hebei Medical University, Shijiazhuang and China
  Pingyangmycin Emulsion Influencing on Microenvironment of Infantile Proliferating Capillary Hemangiomas
    Objective To explore pingyang mycin(PYM) emulsion influencing on the microenvironment of infantile proliferating capillary hemangiomas so as to find the optimal method for hemangiomas’ treatment. Methods Thirty samples of infantile proliferating hemangio...
    2007 Vol. 34 (9): 690-692 [Abstract ] ( 139 ) [HTML 0KB] [PDF 0KB ]( 0 )
693 LIU Fan-rong, ZHONG Qing-ling, XIONG Xiao-liang, ZHU Jing, SONG En-lin, WEN WenDepartment of Pathology, Medical College of Nanchang University, Nanchang , China, Department of Pathology and The Second Peoples Hospital of Shenzhen
  Immunophenotype and Epstein-Barr Virus Infection and Detection Rearrangement of T Cell Receptor γ(TCRγ) Gene in Nasal NK/T-cell Lymphoma
    Objective To explore the immunophenotype and Epstein-Barr Virus(EBV) infection of nasal NK/T cell lymphoma and the significance of detection rearrangement of TCR γ gene in diagnosis and differential diagnosis of nasal NK/T cell lymphoma. Methods Fouty-ei...
    2007 Vol. 34 (9): 693-695 [Abstract ] ( 117 ) [HTML 0KB] [PDF 0KB ]( 0 )
696 CHE Yi-qun, WANG Hai, SHI Xue-dong, QI Jun, GUO Jian, LIU Zhi-hua Department of Clinical Laboratory, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing , China, Department of Clinical Laboratory, China-Japan Union Hospital of Jilin University, National Center for Clinical Laboratory, Ministry of Health of the PR China, National Laboratory of Molecular Oncology, Cancer Institute amp, Hospital, Chinese Academy of Medical Sciences amp and Peking Union Med
  Differential Expression of SPARC in Laryngeal Squamous Cell Carcinoma
    Objective To investigate the role of secreted protein, acidic and rich in cysteine (SPARC) in proliferation and metastasis of laryngeal squamous cell carcinoma (LSCC). Methods The differential gene expression of SPARC between laryngeal squamous cell carci...
    2007 Vol. 34 (9): 696-698 [Abstract ] ( 159 ) [HTML 0KB] [PDF 0KB ]( 0 )
699 HE Yan-jiao, LIU Zhao-xia, LI Hong-li, YU Jin, LI GuangDepartment of Pathology, Beijing Tiantan Hospital, Beijing and China
  Expression and Significance of E-cadherin and Ki-67 in Colorectal Carcinoma
    Objective To study the expression and significance of E-cadherin and Ki-67 in colorectal carcinoma. Methods Forty-eight colorectal carcinomas,23 colorectal adenoma and 20 normal colorectal tissues were envolled in this study. Immunohistochemistry method w...
    2007 Vol. 34 (9): 699-702 [Abstract ] ( 165 ) [HTML 0KB] [PDF 0KB ]( 0 )
703 YAO Nan, GAO Qian, WANG Fang, ZOU Ying-ying, GUO PingDepartment of Pathology, Kunming Medical College, Yunnan and China
  Expression of Caudal-Relatedhomeodomain Transcription 2 (CDX2) in Human Colorectal Tumors
    Objective To investigate the effect of CDX2 protein in the carcinogenesis, progression, invasion and metastasis of human colorectal adenocarcinomas and identify its relation to the clinicopathological indices of colorectal adenocarcinoma. Methods CDX2 pro...
    2007 Vol. 34 (9): 703-705 [Abstract ] ( 128 ) [HTML 0KB] [PDF 0KB ]( 0 )
短篇个案
 
 
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    2007 Vol. 34 (9): 689-689 [Abstract ] ( 144 ) [HTML 0KB] [PDF 0KB ]( 0 )
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    2007 Vol. 34 (9): 734-735 [Abstract ] ( 128 ) [HTML 0KB] [PDF 0KB ]( 0 )
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    2007 Vol. 34 (9): 735-735 [Abstract ] ( 123 ) [HTML 0KB] [PDF 0KB ]( 0 )
临床应用
 
 
706 LU Hong, FAN Qing-xia, WANG Rui-lin, WANG Liu-xingDepartment of Oncology, The First Affiliated Hospital, Oncology Center, Zhengzhou University, Zhengzhou and China
  Clinical Significance of Insulin with Combination Chemotherapy in Treation of Malignant Tumor
    Objective To research the synergism and attenuation of insulin on chemotherapy of malignant tumor.Methods Fifty cases of tumor patients in alimentary canal were divided into two groups (experiment group and control group),two cycle chemotherapies of DLF s...
    2007 Vol. 34 (9): 706-707 [Abstract ] ( 139 ) [HTML 0KB] [PDF 0KB ]( 0 )
708 LIU Lin, GUO Jun, CHEN Zhen, WANG Zhe-haiInternal Medicine Third, Shandong Tumor Hospital, Ji nan and China
  Clinical Observation of Taxotere in Combination with 5-Fluorouracil,Leucovorin and Oxaliplatin for Hepatic Metastasis of Gastric Cancer
    Objective To evaluate the effects and adverse reactions of taxotere in Combination with 5-Fluorouracil、Leucovorin and Oxaliplatin regimen for patients with a hepatic metastasis of Gastric Cancer. Methods Taxotere 50 mg/ m2 iv d1, continuous, 5-FU 750 mg/...
    2007 Vol. 34 (9): 708-710 [Abstract ] ( 131 ) [HTML 0KB] [PDF 0KB ]( 0 )
711 WU Jian-bing, WANG Han-jiao, WANG Shun-jin, LI Lin, FENG LongDepartment of Oncology, The Second Affiliated Hospital of Nanchang University, Nanchang and China
  Comparison of Raltitrexed Plus Oxaliplatinl and 5-Fluorouracil/Leucovorin Plus Oxaliplatinl in Treatment of Advanced Colorectal Carcinoma
    Objective The aim of the study was to assess the effect and security of raltitrexed with oxaliplatinl in the treatment of advanced colorectal carcinoma. Methods Forty cases of advanced colorectal cancer were divided into two groups, 20 cases in group A we...
    2007 Vol. 34 (9): 711-713 [Abstract ] ( 119 ) [HTML 0KB] [PDF 0KB ]( 0 )
714 JIANG Hua, LIU Yan-wen, JIANG Wei-meiDepartment of Medical Oncology, Lianyungang Cancer Hospital, Lianyungang and China
  Chronomodulated Infusion of Cisplatin
    Objective To investigate whether chronotherapy can reduce the toxicities caused by cisplatin. Methods From April 2004 to March 2006,29 cases received cisplatin-based regimens by multichannel, programmable pumps as group A. Cisplatin was given in 20 mg/(m2...
    2007 Vol. 34 (9): 714-715 [Abstract ] ( 141 ) [HTML 0KB] [PDF 0KB ]( 0 )
流行病学
 
 
716 KAN Xiang-Xu, ZOU Tian-Ning, WU Xia-Yu, WANG XuSchool of Life Sciences, Yunnan Normal University, Kunming , China and Third Affiliated Hospital of Kunming Medical College
  Association between MTHFR Genotype Polymorphism and Breast Cancer Susceptibility in Human Population from Yunnan
    Objective Background & Objective Methylenetetrahydroflate reductase gene (MTHFR) encodes MTHFR which is critical for folic acid metabolism.The polymorphisms of MTHFR may affect the outcome of folic acid metabolism. The research aimed at comparing the ...
    2007 Vol. 34 (9): 716-718 [Abstract ] ( 146 ) [HTML 0KB] [PDF 0KB ]( 0 )
研究简报
 
 
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    2007 Vol. 34 (9): 719-720 [Abstract ] ( 134 ) [HTML 0KB] [PDF 0KB ]( 0 )
综述
 
 
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    2007 Vol. 34 (9): 721-723 [Abstract ] ( 170 ) [HTML 0KB] [PDF 0KB ]( 0 )
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    2007 Vol. 34 (9): 724-726 [Abstract ] ( 180 ) [HTML 0KB] [PDF 0KB ]( 0 )
技术交流
 
 
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    2007 Vol. 34 (9): 727-729 [Abstract ] ( 129 ) [HTML 0KB] [PDF 0KB ]( 0 )
论著摘要
 
 
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    2007 Vol. 34 (9): 730-731 [Abstract ] ( 122 ) [HTML 0KB] [PDF 0KB ]( 0 )
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    2007 Vol. 34 (9): 731-732 [Abstract ] ( 121 ) [HTML 0KB] [PDF 0KB ]( 0 )
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