| Citation: |
ZHENG Zheng, ZOU Changpeng, ZHAO Liping, TIAN Bo, BO Changwen, AN Yonghui, LI Na, LIANG Xianwei, GUO Ying. Curative Effect of Argon-helium Cryoablation on Maxillary Sinus Cancer[J]. Cancer Research on Prevention and Treatment, 2020, 47(7): 536-541. DOI: 10.3971/j.issn.1000-8578.2020.19.1460
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Objective To investigate the effect of argon-helium cryoablation on maxillary sinus cancer and its influence on immune function, IL-6, TNF-α, TNF–β and INF-γ.
From August 2012 to August 2016, 37 patients with maxillary sinus cancer treated by argon-helium cryoablation were selected as the observation group, and 35 patients treated with traditional surgery and local radiotherapy were selected as the control group at the same time. The short- and long-term effects, the changes of immune energy and verification factors before and after operation were recorded and followed up.
The effective rates of treatment in the observation group and the control group were 56.75% and 60.00%, respectively. CD8+ decreased and CD4+/CD8+ increased in two groups after operation (P < 0.05). The levels of IL-6, TNF-α, TNF–β and INF-γ in the serum of patients at different stages after operation were lower than those before operation (P < 0.05).
Methods Results Conclusion Targeted argon-helium cryoablation can improve the immune function and inflammatory response of patients with maxillary sinus cancer, with less complications and good long-term effect.
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