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LI Bingtai, KOU Bangguo, JIANG Yongjie, BIAN Pan, YIN Lanning. Anti-tumor Drug Delivery and Tumor Therapy Based on Metal-organic Frameworks[J]. Cancer Research on Prevention and Treatment, 2022, 49(8): 832-837. DOI: 10.3971/j.issn.1000-8578.2022.21.1457
Citation: LI Bingtai, KOU Bangguo, JIANG Yongjie, BIAN Pan, YIN Lanning. Anti-tumor Drug Delivery and Tumor Therapy Based on Metal-organic Frameworks[J]. Cancer Research on Prevention and Treatment, 2022, 49(8): 832-837. DOI: 10.3971/j.issn.1000-8578.2022.21.1457

Anti-tumor Drug Delivery and Tumor Therapy Based on Metal-organic Frameworks

  • Metal-organic frameworks (MOFs) are mixed porous materials which are composed of metal clusters or ions and organic pillars. Given their channel tunability, high porosity, large specific surface area, and good biocompatibility, MOFs can be combined with various biological macromolecules. In recent years, they have been widely studied in the field of biomedicine, especially in the loading of anti-tumor drugs, showing great application prospects. Multifunctional anti-tumor MOF combined with different therapeutic methods provides a new idea and method for tumor treatment. On the basis of the structure of MOF, this paper introduces the advantages of using MOF to load anti-tumor drugs and reviews the application of MOF in tumor therapy.
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