Cancer Research on Prevention and Treatment    2022, Vol. 49 Issue (09) : 982-986     DOI: 10.3971/j.issn.1000-8578.2022.22.0064
Neoadjuvant Treatment of Borderline Resectable Pancreatic Cancer
CHEN Zegang1, WANG Yongbing1, OU Tao2
1. Department of Oncology, Chongqing Liangping District People’s Hospital, Chongqing 405200, China; 2. Center of Cancer Radiotherapy, Chongqing University Cancer Hospital, Chongqing 400000, China
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Abstract Borderline resectable pancreatic ductal adenocarcinoma accounts for approximately 20% of newly diagnosed pancreatic cancer patients. This type of adenocarcinoma is between resectable and unresectable. It has a high degree of heterogeneity and features in anatomy, biology, and physical condition. The biological characteristics of invasiveness determine that, rather than direct surgery, neoadjuvant therapy should be primarily given to patients to achieve R0 resection and avoid early postoperative recurrence. However, this treatment model is still controversial. According to the latest research on this topic, the full text summarizes the definition of BR-PDAC, resectable evaluation, neoadjuvant treatment selection and evaluation, surgical results after neoadjuvant therapy, and the efficacy of adjuvant therapy after neoadjuvant therapy.
Keywords Pancreatic ductal adenocarcinoma      Borderline resectable pancreatic cancer      Neoadjuvant therapy      Operation      Chemotherapy      Radiotherapy     
ZTFLH:  R735.9  
Fund:Chongqing Science and Health Joint Medical Research Project (No. 2021MSXM289)
Issue Date: 15 September 2022
 Cite this article:   
CHEN Zegang,WANG Yongbing,OU Tao. Neoadjuvant Treatment of Borderline Resectable Pancreatic Cancer[J]. Cancer Research on Prevention and Treatment, 2022, 49(09): 982-986.
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OU Tao
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